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Diamorphine Supply Issues - Updated Information

Thursday, June 21, 2018


A latest news story was published on our website on the 28th May on Diamorphine Supply Issues. We now have some additional information for you which you can view below.

Background

There are currently two suppliers of diamorphine injection in the UK; Accord and Wockhardt. Recently Accord’s supplier in Germany experienced quality issues and UK Gov have since been working with Accord. They have now advised, that the manufacture of diamorphine 5mg and 10mg injection will soon resume, with an anticipated resupply date of beginning of September 2018.

To support this supply this issue, Wockhardt have increased their production of diamorphine 5mg and 10mg, but are unable to support the entire market in July and August. However primary care supplies have been ring fenced.

Your support with this shortage is greatly appreciated and in order to help manage this shortage please follows the guidelines below:-

Primary Care

There are no restrictions on access to diamorphine 5mg and 10mg. Please however order responsibly during this time, in line with historical demand, and do not stockpile to avoid lengthening the stock out period

Ordering

  • Diamorphine 5mg and 10mg will only be available to order from Alliance. No minimum surcharges will be levied for this product.
  • Morphine 10mg injection (Martindale) available to order from AAH only.
  • Diamorphine 30mg injection, 100mg and 500mg are available from the usual wholesalers.

Alternative Opioids

Morphine injection is the recommended alternative.  There should also be sufficient fentanyl and oxycodone injections to support this supply issue if clinician preference is for one of these 2 agents.

The Department of Health and Social Care have provided notification of a manufacturing problem with Diamorphine 5mg and 10mg injection. There are currently two suppliers of Diamorphine injection in the UK; Accord and Wockhardt. Recently Accord’s plant in Germany has experienced quality issues that has temporarily impacted on supply. The Department of Health is working closely with Accord, regulators, and others in the resolution of these issues.

Based on current usage, there is the potential for supplies of Diamorphine 5mg and 10mg injection to be depleted around the week commencing 4th June 2018 and for there to be a gap in supply until the 28th June 2018. Further patient information is available.

NHS Advice:

  • Please order responsibly during this time, in line with historical demand, and do not stockpile to avoid lengthening the stock out period.
  • The recommended alternative is morphine injection.  Morphine 10mg injection will be available to cover the Diamorphine supply issue in June. Please only order extra stock of Morphine as Diamorphine injection becomes unavailable locally and do not stock pile.  

Guidance